Ivermectin is the new hydroxychloroquine, take 7: Are there positive studies that aren't fraudulent? - 2021-10-18

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F0.png Ivermectin is the new hydroxychloroquine, take 7: Are there positive studies that aren't fraudulent? October 18, 2021, Orac, Respectful Insolence

I've long been saying that ivermectin is the new hydroxychloroquine, so much so that I have to say now that ivermectin is no longer new, even as I speculate what new "miracle cure" for COVID-19 will become the "new ivermectin". Readers might remember that, very early in the pandemic, hydroxychloroquine, a widely used antimalarial drug with mild immunosuppressive properties that make it also useful to treat some autoimmune diseases, was seized upon as the (then) only effective treatment for COVID-19 based on reported observations in Wuhan, China during the first major outbreak. There, a group of Chinese researchers reported that none of a group of their 80 patients with lupus erythematosus who were taking hydroxychloroquine went on to become infected with SARS-CoV-2. Based on that very thin gruel, hydroxychloroquine for a time became part of the de facto standard of care around the world, including in one of the hospitals that I practice at. The devotion to hydroxychloroquine spread, thanks to promotion by Dr. Oz, then-President Donald Trump, and a veritable rogues' gallery of quacks, and it took a long time for the evidence to catch up and kill it. There was a reason why I called hydroxychloroquine the Black Knight of COVID-19 treatments, because no amount of evidence appeared able to kill it, until it did. Even so, a year later there remains a contingent of quacks who still promote it not just as a treatment but as a preventative.

At the time, at least early last year, I could understand why so many doctors latched onto hydroxychloroquine. After all, patients were getting deathly ill and dying in droves, and they didn't know what to do beyond supportive care that tried to keep them from dying long enough to clear the infection. Under circumstances like those, it's human nature to try something like hydroxychloroquine, nor was it unethical then, at least initially, to try it, at least until there was more evidence. These days, not so much. We know hydroxychloroquine doesn't work, and there are vaccines and potential treatments.

Enter ivermectin, an anthelmintic drug commonly used around the world to treat diseases caused by parasitic roundworms in both animals and humans. Based on a recent BBC news report, Ivermectin: How false science created a Covid 'miracle' drug, it's looking more and more as though the clinical trial base for the drug as a treatment for COVID-19 is almost all either fraudulent or so badly done that it might as well be fraudulent. Given the publication of that news report, now seems to be as good a time as any to revisit ivermectin and look at the massive fraud that's fueled massive grift and many conspiracy theories.

Wikipedia cite:
{{cite news | author = Orac | title = Ivermectin is the new hydroxychloroquine, take 7: Are there positive studies that aren't fraudulent? | url = https://respectfulinsolence.com/2021/10/18/ivermectin-is-the-new-hydroxychloroquine-take-7/ | work = Respectful Insolence | date = October 18, 2021 | accessdate = October 18, 2021 }}